MONDAY, March 18, 2024-- The U.S. Food and Drug Administration has approved Breyanzi (lisocabtagene maraleucel [liso-cel]) as the first CD19-directed chimeric antigen receptor (CAR) T-cell therapy for adult patients with relapsed or refractory...
https://www.drugs.com/news/fda-approves-first-car-t-cell-therapy-adults-leukemia-lymphoma-118226.htmlMONDAY, March 18, 2024-- Childhood lead exposure is widespread in Chicago and there are racial inequities evident in testing rates and exposure levels, according to a study published online March 18 in JAMA Pediatrics.Benjamin Q. Huynh, Ph.D.,...
https://www.drugs.com/news/childhood-lead-exposure-widespread-chicago-118227.htmlMONDAY, March 18, 2024 -- There is little to no difference in the effectiveness of in-person versus therapist-guided remote cognitive behavioral therapy (CBT) across a range of mental health and somatic disorders, according to a review published in...
https://www.drugs.com/news/person-remote-cognitive-behavioral-therapy-similarly-effective-118216.htmlMONDAY, March 18, 2024 -- Some U.S. government personnel have reported dizziness, pain, visual problems, and cognitive dysfunction after experiencing intrusive sounds and head pressure, termed anomalous health incidents (AHIs), but no differences...
https://www.drugs.com/news/studies-explore-anomalous-health-incidents-reported-government-personnel-118217.htmlMONDAY, March 18, 2024 -- Polygenic risk scores (PRSs) derived from the general population are associated with a subsequent risk for certain cancers among survivors of childhood cancer, with an additive risk for PRS and radiotherapy, according to a...
https://www.drugs.com/news/genetic-factors-influence-subsequent-cancer-risk-childhood-cancer-survivors-118219.htmlMONDAY, March 18, 2024 -- Participation in the Community Eligibility Provision (CEP) universal free school meals program reduces the prevalence of obesity among students, according to a study published online March 18 in Pediatrics.Anna M....
https://www.drugs.com/news/participation-free-school-meals-program-cuts-obesity-prevalence-118218.htmlMONDAY, March 18, 2024 -- In a report published in the April issue of Emerging Infectious Diseases, the details of 10 cases of nonkeratitis Acanthamoeba infection are described from 1994 to 2022, all of which occurred among immunocompromised...
https://www.drugs.com/news/study-addresses-nasal-rinsing-nonkeratitis-acanthamoeba-infection-118220.htmlMONDAY, March 18, 2024 -- For people with HIV (PWH) with metabolic-associated steatotic liver disease (MASLD), semaglutide is associated with absolute and relative declines in intrahepatic triglyceride (IHTG) content, according to a study presented...
https://www.drugs.com/news/glp-1-ra-reduces-severity-steatotic-liver-hiv-118221.htmlMONDAY, March 18, 2024 -- A number of children with sickle cell anemia (SCA) have low rates of receipt of recommended antibiotic prophylaxis and annual transcranial Doppler (TCD) ultrasound, according to a study published online March 6 in...
https://www.drugs.com/news/many-children-sickle-cell-anemia-do-not-meet-quality-indicators-118225.htmlMONDAY, March 18, 2024 -- In a clinical guideline issued by the American College of Gastroenterology and published online in the March issue of the American Journal of Gastroenterology, evidence-based recommendations are presented for the management...
https://www.drugs.com/news/evidence-based-approach-recommended-acute-pancreatitis-management-118224.htmlMONDAY, March 18, 2024 -- Lebrikizumab demonstrates improvement in skin clearance and itch relief in patients with skin of color and moderate-to-severe atopic dermatitis, according to a study presented at the annual meeting of the American Academy...
https://www.drugs.com/news/aad-lebrikizumab-shows-efficacy-skin-color-patients-atopic-dermatitis-118222.htmlMONDAY, March 18, 2024 -- Continuous treatment with baricitinib in patients with severe alopecia areata demonstrates improvement in hair regrowth outcomes through 76 weeks of follow-up, according to a study presented at the annual meeting of...
https://www.drugs.com/news/aad-hair-regrowth-continues-improve-76-weeks-baricitinib-severe-alopecia-118223.htmlFRIDAY, March 15, 2024 -- Teen pregnancy is associated with future premature mortality, according to a study published online March 14 in JAMA Network Open.Joel G. Ray, M.D., from the University of Toronto, and colleagues examined the risk of...
https://www.drugs.com/news/teen-pregnancy-linked-future-premature-mortality-118200.htmlFRIDAY, March 15, 2024 -- A single-session mindfulness and compassion intervention may lead to meaningful reductions in perceived stress and symptoms of anxiety and depression, according to a study published online March 13 in PLOS ONE.Mikael...
https://www.drugs.com/news/single-mindfulness-compassion-session-aids-mental-health-118203.htmlFRIDAY, March 15, 2024 -- On Thursday, the U.S. Food and Drug Administration announced the approval of Rezdiffra (resmetirom) to treat noncirrhotic nonalcoholic steatohepatitis (NASH) with moderate-to-advanced fibrosis."Previously, patients with...
https://www.drugs.com/news/fda-approves-rezdiffra-first-specific-nonalcoholic-steatohepatitis-118202.htmlFRIDAY, March 15, 2024 -- In-person schooling and coping behaviors were associated with higher positive affect (PA) during the COVID-19 pandemic among adolescents with high adverse childhood experiences (ACEs; at least four), according to a study...
https://www.drugs.com/news/coping-behaviors-improved-mental-well-being-adversity-exposed-teens-during-pandemic-118201.htmlFRIDAY, March 15, 2024 -- There is a significant association between depression and subsequent cardiovascular disease (CVD) events in both men and women, according to a study published online March 12 in JACC: Asia.Keitaro Senoo, M.D., from...
https://www.drugs.com/news/depression-tied-higher-risk-cvd-events-both-men-women-118204.htmlFRIDAY, March 15, 2024 -- Associations between adverse childhood experiences (ACEs) and adult mental health outcomes remain significant even after controlling for shared genetic and environmental factors, according to a study published online March...
https://www.drugs.com/news/adverse-childhood-experiences-tied-adult-mental-health-outcomes-118198.htmlFRIDAY, March 15, 2024 -- Short-term exposure to wildfire-related air pollution is associated with an increase in clinic visits for acne vulgaris among adults, according to a study presented at the annual meeting of the American Academy of...
https://www.drugs.com/news/aad-adult-acne-clinic-visits-increase-exposure-wildfire-related-air-pollution-118192.htmlFRIDAY, March 15, 2024 -- Patients with psoriasis treated with bimekizumab rapidly achieve high levels of clinical and health-related quality-of-life responses that are durable at four years, according to research presented at the annual...
https://www.drugs.com/news/aad-bimekizumab-response-durable-four-years-moderate-severe-psoriasis-118196.htmlFRIDAY, March 15, 2024 -- Any amount of activity above 2,200 steps per day is associated with lower mortality and cardiovascular disease (CVD) risk, regardless of sedentary time, according to a study published online March 5 in the British...
https://www.drugs.com/news/2-200-minimum-number-daily-steps-needed-lower-death-cvd-risk-118195.htmlFRIDAY, March 15, 2024 -- About one-quarter of pregnant women rarely or never consume fish during pregnancy, and few use omega-3 supplements, according to a study published online Feb. 27 in Public Health Nutrition.Emily Oken, M.D., M.P.H., from...
https://www.drugs.com/news/one-quarter-pregnant-women-rarely-never-consume-fish-118199.htmlFRIDAY, March 15, 2024 -- Lateral extra-articular tenodesis (LET) and anterolateral ligament reconstruction (ALLR) techniques for the treatment of anterior cruciate ligament in skeletally immature patients show promising results, according to a...
https://www.drugs.com/news/review-ids-trends-anterior-cruciate-ligament-injury-treatments-children-118197.htmlFRIDAY, March 15, 2024 -- A cell-free DNA (cfDNA) blood-based test has sensitivity of 83.1 percent for detection of colorectal cancer and specificity of 89.6 percent for any advanced neoplasia, according to a study published in the March 14 issue of...
https://www.drugs.com/news/cell-free-dna-test-has-83-1-percent-sensitivity-detection-crc-118191.htmlFRIDAY, March 15, 2024 -- Conditions affecting the nervous system were collectively ranked as the leading group cause of disability-adjusted life years (DALYs) in 2021, according to a study published online March 14 in The Lancet Neurology.Jaimie...
https://www.drugs.com/news/neurological-conditions-ranked-leading-cause-dalys-globally-118194.htmlFRIDAY, March 15, 2024 -- Living in a neighborhood with greater poverty in adulthood is tied to lower ovarian reserve, according to a study published online March 5 in Menopause.Anwesha Pan, from the University of Washington in Seattle, and...
https://www.drugs.com/news/neighborhood-poverty-may-impact-women-s-ovarian-reserves-118193.htmlTHURSDAY, March 14, 2024 -- Among primary care patients in the United Kingdom, the incidence of prostate cancer with an elevated prostate-specific antigen (PSA) result is higher among Black men than White or Asian men, according to a study published...
https://www.drugs.com/news/black-men-face-highest-incidence-prostate-cancer-u-k-118180.htmlTHURSDAY, March 14, 2024 -- Among sexual and gender-minority people who initiate preexposure prophylaxis (PrEP) for HIV, the annual rate of discontinuation is between 35 and 40 percent, according to a study published in the March issue of Health...
https://www.drugs.com/news/rate-prep-discontinuation-seen-sexual-gender-minority-118178.htmlTHURSDAY, March 14, 2024 -- In 2023, 117 cases of multisystem inflammation syndrome in children (MIS-C) were reported, with 26 percent of patients having onset during August to October, according to research published in the March 14 issue of the...
https://www.drugs.com/news/one-hundred-seventeen-cases-mis-c-identified-during-2023-118177.htmlTHURSDAY, March 14, 2024 -- The overall number of clinically active rheumatology providers grew more than 20 percent during the last decade, according to a study published online Feb. 25 in Arthritis & Rheumatology.Melissa L. Mannion,...
https://www.drugs.com/news/rheumatology-workforce-increased-20-percent-2009-2019-118179.htmlTHURSDAY, March 14, 2024 -- In 2022, 5.8 percent of children ages 5 to 17 years experienced chronic school absenteeism for health-related reasons, according to a March data brief published by the National Center for Health Statistics.Lindsey I....
https://www.drugs.com/news/chronic-school-absenteeism-5-8-percent-5-17-year-olds-2022-118167.htmlTHURSDAY, March 14, 2024 -- A next-generation multitarget stool DNA test has higher sensitivity for colorectal cancer and advanced precancerous lesions than fecal immunochemical testing (FIT), according to a study published in the March 14 issue of...
https://www.drugs.com/news/multitarget-stool-dna-test-has-higher-sensitivity-crc-than-fit-118169.htmlTHURSDAY, March 14, 2024 -- Adverse pregnancy outcomes related to use of the dapivirine vaginal ring (DVR) or daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) during the second trimester are uncommon, according to a study presented...
https://www.drugs.com/news/dapivirine-vaginal-ring-safe-effective-preventing-hiv-during-pregnancy-118168.htmlTHURSDAY, March 14, 2024 -- Middle-aged veterans with blast-related mild traumatic brain injury (mTBI) have reduced levels of cerebrospinal fluid (CSF) β-amyloid (Aβ), according to a study published online March 13 in Neurology.Ge Li,...
https://www.drugs.com/news/reduced-levels-csf-amyloid-seen-veterans-blast-related-mtbi-118171.htmlTHURSDAY, March 14, 2024 -- For people with stable chest pain referred for invasive coronary angiography (ICA), the risk for major adverse cardiovascular events (MACE) is low among those with a low coronary artery calcium (CAC) score, according to a...
https://www.drugs.com/news/cac-score-predicts-mace-patients-stable-chest-pain-118175.htmlTHURSDAY, March 14, 2024 -- Calls to U.S. poison centers involving psilocybin, or “magic mushrooms,” among adolescents and young adults rose sharply starting in 2019, according to a study published online Feb. 26 in the Journal of...
https://www.drugs.com/news/poison-center-calls-magic-mushrooms-spiked-starting-2019-118174.htmlTHURSDAY, March 14, 2024 -- Spring daylight saving time (DST) transitions may be associated with a minor increase in adverse cardiovascular event rates, according to a study published online in the February issue of Mayo Clinic Proceedings:...
https://www.drugs.com/news/spring-daylight-savings-transition-tied-increase-cardiovascular-events-118172.htmlTHURSDAY, March 14, 2024 -- There has been a widening of racial and ethnic relative disparities in the pollution-attributable health burden within the United States, according to a study published online March 6 in Environmental Health...
https://www.drugs.com/news/widening-disparities-pollution-attributed-health-burden-observed-118173.htmlTHURSDAY, March 14, 2024 -- Pregnant women receiving the respiratory syncytial virus (RSV) prefusion F protein-based maternal vaccine (RSVPreF3-Mat) have offspring with lower risks for any and severe medically assessed RSV-associated lower...
https://www.drugs.com/news/infant-respiratory-tract-risk-lower-maternal-rsv-vaccine-118170.htmlTHURSDAY, March 14, 2024 -- Lower levels of nurse staffing in the emergency department are associated with adverse events, according to a review published online Feb. 1 in the International Journal of Nursing Studies.Jonathan Drennan, Ph.D.,...
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